LAMTOR1 Antibody, HRP conjugatedСпецификация| Объем | 100 мкг | | Синонимы | Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho), LAMTOR1, C11orf59 PDRO | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q6IAA8 | | Иммуноген | Recombinant Human Ragulator complex protein LAMTOR1 protein (2-161AA) | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA | | Примечание | As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulator complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | HRP | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | Ragulator complex protein LAMTOR1 | | Области исследований | Cardiovascular, Metabolism, Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкг | | Кат. номер: | CSB-PA757083LB01HU | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: LAMTOR1 Antibody, HRP conjugated.
Примечание: дополнительная информация (на английском языке). |
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