Объем | 100 мкл |
Синонимы | Cancer/testis antigen 10, CT10, HCA587, hepatocellular cancer antigen 587, Hepatocellular carcinoma-associated antigen 587 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9UBF1 |
Иммуноген | Synthesized peptide derived from internal of human MAGEC2. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.<br/><br/>Gure A.O., Int. J. Cancer 85:726-732(2000) [PubMed: 10699956].<br/>Lucas S., Int. J. Cancer 87:55-60(2000) [PubMed: 10861452].<br/>Wang Y., J. Immunol. 169:1102-1109(2002) [PubMed: 12097419].<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cancer,Immunology |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells, using MAGEC2 antibody.
|
| |