MASTL Antibody, Biotin conjugated

Спецификация

Объем	100 мкг
Синонимы	Serine/threonine-protein kinase greatwall (GW) (GWL) (hGWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L), MASTL, GW GWL THC2
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q96GX5
Иммуноген	Recombinant Human Serine/threonine-protein kinase greatwall protein (612-740AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. Phosphorylates histone protein in vitro, however such activity is unsure in vivo. May be involved in megakaryocyte differentiation.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Serine/threonine-protein kinase greatwall
Области исследований	Signal transduction
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкг
	Кат. номер:	CSB-PA846629LD01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: MASTL Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).