| Объем | 50 мкл |
| Синонимы | minichromosome maintenance complex component 7 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P33993 |
| Иммуноген | Fusion protein of human MCM7 |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:15-1:50 |
| Примечание | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA811751(MCM7 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ?200)
 |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA811751(MCM7 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ?200)
 |
Gel: 10%SDS-PAGE, Lysate: 50 ?g, Lane: Jurkat cells, Primary antibody: CSB-PA811751(MCM7 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
 |
| | |
Наименование: MCM7 Antibody.