Объем | 50 мкг |
Синонимы | Meiosis-specific kinetochore protein, MEIKIN |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | A0A087WXM9 |
Иммуноген | Recombinant Human Meiosis-specific kinetochore protein (18-91AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IHC, Recommended dilution: IHC:1:20-1:200 |
Примечание | Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase-mediated cleavage. Acts by facilitating kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent protection pathway. Acts in collaboration with PLK1: required for PLK1 enrichment to kinetochores. Not required during meiosis II or mitosis. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Meiosis-specific kinetochore protein |
Области исследований | Others |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA20649A0Rb at dilution of 1:100
|
| |