Объем | 100 мкл |
Синонимы | Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1), MLF1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P58340 |
Иммуноген | Recombinant Human Myeloid leukemia factor 1 protein (1-268AA) |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, Recommended dilution: WB:1:1000-1:5000 |
Примечание | Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Абревеатура | Myeloid leukemia factor 1 |
Области исследований | Cardiovascular, Cell biology, Tags & Cell Markers, Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: MLF1 antibody at 2.94µg/ml + Mouse brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 31, 24, 34, 28, 30 kDa
Observed band size: 31 kDa
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