MRC2 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Macrophage mannose receptor 2 [Precursor], Urokinase receptor-associated protein, Endocytic receptor 180, CD280 antigen, MRC2 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9UBG0 | | Иммуноген | Synthesized peptide derived from internal of human MRC2. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 | | Примечание | May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).<br/><br/>Behrendt N., J. Biol. Chem. 275:1993-2002(2000).<br/>Sheikh H., J. Cell Sci. 113:1021-1032(2000).<br/>Howard M.J., J. Biol. Chem. 277:32320-32331(2002).<br/> <br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cell biology | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from 293 cells, using MRC2 antibody.
 | Immunohistochemistry analysis of paraffin-embedded human brain tissue using MRC2 antibody.
 | Immunofluorescence analysis of HepG2 cells, using MRC2 antibody.
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Наименование: MRC2 Antibody.