MRPS18C AntibodyСпецификацияОбъем | 100 мкл | Синонимы | 28S ribosomal protein S18c, mitochondrial, MRP-S18-1, MRP-S18-c, RT18C | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9Y3D5 | Иммуноген | Synthesized peptide derived from internal of human MRPS18C. | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 | Примечание | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q.<br/><br/>Lai C.-H., Genome Res. 10:703-713(2000).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/>Koc E.C., J. Biol. Chem. 276:19363-19374(2001). | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Epigenetics and Nuclear Signaling,Tags & Cell Markers | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from K562 cells, using MRPS18C antibody.
| Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue using MRPS18C antibody.
| Immunofluorescence analysis of MCF-7 cells, using MRPS18C antibody.
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