NANOG Antibody, FITC conjugated

Спецификация

Объем	100 мкг
Синонимы	Homeobox protein NANOG (Homeobox transcription factor Nanog) (hNanog), NANOG
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q9H9S0
Иммуноген	Recombinant Human Homeobox protein NANOG protein (1-305AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression. When overexpressed, promotes cells to enter into S phase and proliferation.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	FITC
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Области исследований	Epigenetics and Nuclear Signaling, Cancer, Developmental biology, Stem cells
Ссылка на страницу на сайте производителя	ссылка

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкг
	Кат. номер:	CSB-PA888008LC01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: NANOG Antibody, FITC conjugated. Примечание: дополнительная информация (на английском языке).