| Объем | 100 мкл |
| Синонимы | HEC1, HEC, Highly expressed in cancer, rich in leucine heptad repeats, KNTC2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O14777 |
| Иммуноген | Synthesized peptide derived from internal of human KNTC2. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 |
| Примечание | Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.<br/><br/>Chen Y., Mol. Cell. Biol. 17:6049-6056(1997).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/>Zheng L., Mol. Cell. Biol. 19:5417-5428(1999).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using KNTC2 antibody.
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Immunofluorescence analysis of HUVEC cells, using KNTC2 antibody.
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Наименование: NDC80 Antibody.