NPR1 AntibodyСпецификация| Объем | 50 мкл | | Синонимы | Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P16066 | | Иммуноген | Synthetic peptide of human NPR1 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, IHC,ELISA:1:1000-1:5000, IHC:1:25-1:100 | | Примечание | Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms . The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides, they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2, MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Cardiovascular,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA090777(NPR1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | | | |
Информация для заказа |
Наименование: NPR1 Antibody.