NR3C1 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | nuclear receptor subfamily 3, group C, member 1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P04150 | Иммуноген | Fusion protein of human NR3C1 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 | Примечание | This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA225804(NR3C1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ?200)
| The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA225804(NR3C1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ?200)
| Gel: 6%SDS-PAGE, Lysate: 40 ?g, Lane 1-3: Jurkat cells, A172 cells, mouse brain tissue, Primary antibody: CSB-PA225804(NR3C1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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