NR3C1 Antibody, HRP conjugated

Спецификация

Объем	50 мкг
Синонимы	Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1), NR3C1, GRL
Клональность	Polyclonal Antibody
Организм	Human
uniprot	P04150
Иммуноген	Recombinant Human Glucocorticoid receptor protein (1-190AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Receptor for glucocorticoids (GC) (PubMed:27120390). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling (PubMed:9590696). Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay (PubMed:25775514). Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth (By similarity).
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	HRP
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Glucocorticoid receptor
Области исследований	Epigenetics and Nuclear Signaling, Cancer, Signal transduction
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA016059LB01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: NR3C1 Antibody, HRP conjugated. Примечание: дополнительная информация (на английском языке).