Outer capsid protein VP4 AntibodyСпецификация| Объем | 50 мкг | | Синонимы | Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8~X, Outer capsid protein VP5~X] | | Клональность | Polyclonal Antibody | | Организм | Rotavirus A | | uniprot | P11200 | | Иммуноген | Recombinant Rotavirus A Outer capsid protein VP4 protein (247-479AA) | | Источник | Rabbit | | Видовая специфичность | Rotavirus A | | Применение | ELISA | | Примечание | Spike-forming protein that mediates virion attachment to the host epithelial cell receptors and plays a major role in cell penetration, determination of host range restriction and virulence. Rotavirus entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. According to the considered strain, VP4 seems to essentially target sialic acid and/or the integrin heterodimer ITGA2/ITGB1 (By similarity).By similarity Outer capsid protein VP5~X: forms the spike "foot" and "body". Acts as a membrane permeabilization protein that mediates release of viral particles from endosomal compartments into the cytoplasm. In integrin-dependent strains, VP5~X targets the integrin heterodimer ITGA2/ITGB1 for cell attachment (By similarity).By similarity VP8~X forms the head of the spikes. It is the viral hemagglutinin and an important target of neutralizing antibodies. In sialic acid-dependent strains, VP8~X binds to host cell sialic acid, most probably a ganglioside, providing the initial contact (By similarity). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | Outer capsid protein VP4 | | Области исследований | Others | | Ссылка на страницу на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 50 мкг | | Кат. номер: | CSB-PA320838LA01ROH | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Outer capsid protein VP4 Antibody.
Примечание: дополнительная информация (на английском языке). |
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