Объем | 100 мкл |
Синонимы | ADRB2R, B2AR, adrenergic receptor, beta-2, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P07550 |
Иммуноген | Peptide sequence around phosphorylation site of serine 346 (R-S-S(p)-L-K) derived from Human Adrenergic Receptor beta2. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:1000 |
Примечание | <p>Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.<br /><br />Gao S, Malbon C, Wang HY (2014) J Mol Signal 9, 3 <br />24690384 Curated Info<br />Vistein R, Puthenveedu MA (2013) Proc Natl Acad Sci U S A 110, 15289-94 <br />Gimenez LE, et al. (2012) J Biol Chem 287, 9028-40</p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Ser346 |
Области исследований | Cardiovascular,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells treated with Nocodazole using Phospho-Adrenergic Receptor beta2 (Ser346) antibody.The lane on the right is treated with the antigen-specific peptide.
|
| |