Phospho-CD44 (Ser706) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CD44 antigen precursor, ECMR-III, Epican, Hermes antigen, PGP-1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P16070 | | Иммуноген | Peptide sequence around phosphorylation site of serine 706 (S-K-S(p)-Q-E) derived from Human CD44. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | <p>Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.<br/><br/>Ildefonso CJ, et al. (2012)J Biol Chem 287, 32697-707. Pivetta E, et al. (2011)J Cell Physiol 226, 769-79. Wang YT, et al. (2010)J Proteome Res 9, 5582-97.</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Ser706 | | Области исследований | Cancer,Immunology,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from NIH-3T3 cells treated with PMA using Phospho-CD44 (Ser706) antibody.The lane on the right is treated with the antigen-specific peptide.
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA135522 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-CD44 (Ser706) Antibody.
Примечание: дополнительная информация (на английском языке). |
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