Объем | 100 мкл |
Синонимы | CREB |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P16220 |
Иммуноген | Peptide sequence around phosphorylation site of serine 142(D-L-S(p)-S-D) derived from Human CREB. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 |
Примечание | <p> ,Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.</p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Ser142 |
Области исследований | Epigenetics and Nuclear Signaling,Immunology |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CREB (Phospho-Ser142) Antibody.
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Western blot analysis of extracts from 293 cells, treated with calf intestinal phosphatase (CIP), using CREB(Phospho-Ser142) Antibody.
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