Phospho-MEF2A (Ser408) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | MEF2, Serum response factor-like protein 1, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q02078 | | Иммуноген | Peptide sequence around phosphorylation site of serine 408 (P-I-S(p)-P-P) derived from Human MEF2A. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, IHC,IHC:1:50-1:100 | | Примечание | The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain<br/><br/>Okamoto SI, et al. (2002) Proc Natl Acad Sci USA, 99(6): 3974-3979.<br/>Quinn ZA, et al. (2001) Nucleic Acids Res, 29(3): 732-742.<br/>Kato Y, et al. (2000) J Biol Chem. 275(24): 18534-18540.<br/>De Angelis L, et al. (1998) Proc Natl Acad Sci USA, 95(21): 12358-12363.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Ser408 | | Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cardiovascular | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MEF2A(Phospho-Ser408) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA968646 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-MEF2A (Ser408) Antibody.
Примечание: дополнительная информация (на английском языке). |
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