| Объем | 100 мкл |
| Синонимы | PLC-IV, PLC-gamma2, Phospholipase C-gamma-2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P16885 |
| Иммуноген | Peptide sequence around phosphorylation site of tyrosine 1217 (F-L-Y(p)-D-T) derived from Human PLCg2. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, IHC,IHC:1:50-1:100 |
| Примечание | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.<br/><br/>Yue, C. et al. (1998) J. Biol. Chem. 273, 18023-18027. <br/>Yue, C. et al. (2000) J. Biol. Chem. 275, 30220-30225. <br/>Margolis, B. et al. (1989) Cell 57, 1101-1107. <br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Tyr1217 |
| Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PLC-g2(Phospho-Tyr1217) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Наименование: Phospho-PLCG2 (Tyr1217) Antibody.