| Объем | 50 мкл |
| Синонимы | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, RP-C, PPP2CA |
| Тип антител | Recombinant Antibody |
| Species | Human |
| UniProt ID | P67775 |
| Иммуноген | A synthesized peptide derived from human Phospho-PPP2CA (Y307) |
| Видовая специфичность | Human |
| Применение | ELISA, WB, Recommended dilution: WB:1:500-1:5000 |
| Клональность | Monoclonal |
| Изотип | Rabbit IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Affinity-chromatography |
| Области исследований | Signal Transduction |
| Аббревиатура | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform |
| Примечание | PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'. |
| Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in:A549 whole cell lysate(treated with EGF or not)
All lanes:Phospho-PPP2CA antibody at 0.95µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 35 KDa
Observed band size: 35 KDa
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Наименование: Phospho-PPP2CA (Y307) Antibody.