PTK2 (Ab-397) AntibodyСпецификацияОбъем | 100 мкл | Синонимы | FADK, PTK2, FAK1, FRNK, PTK2 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q05397 | Иммуноген | Peptide sequence around aa. 395~399 (D-D-Y-A-E) derived from Human FAK. | Источник | Rabbit | Видовая специфичность | Human, Rat | Применение | ELISA, WB,WB:1:500-1:1000 | Примечание | <p>Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events. <br /><br />von Sengbusch A, et al. (2005) Am J Pathol , 166(2): 585-596 <br />Fornaro M, et al. (2000) Mol Biol Cell , 11(7): 2235-2249 <br />Zhang X, et al. (1999) Proc Natl Acad Sci U S A, 96(16): 9021-9026.</p> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Области исследований | Cancer,Cardiovascular,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extract from HepG2, 293, C6, HUVEC and HT29 cells using FAK(Ab-397) Antibody
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