RAB11FIP2 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | KIAA0941, NRip11, Rab11 family-interacting protein 2, Rab11-FIP2, RFIP2 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q7L804 | Иммуноген | Synthesized peptide derived from internal of human RAB11FIP2. | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, WB,WB:1:500-1:3000 | Примечание | A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.<br/><br/>Nagase T., DNA Res. 6:63-70(1999).<br/>Prekeris R., Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.<br/>Deloukas P., Nature 429:375-381(2004).<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from A549 cells, COLO cells, HUVEC cells and MCF-7 cells, using RAB11FIP2 antibody.
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