| Объем | 100 мкл |
| Синонимы | Ribonucleoside-diphosphate reductase subunit M2 B (EC 1.17.4.1) (TP53-inducible ribonucleotide reductase M2 B) (p53-inducible ribonucleotide reductase small subunit 2-like protein) (p53R2), RRM2B, P53R2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q7LG56 |
| Иммуноген | Recombinant Human Ribonucleoside-diphosphate reductase subunit M2 B protein (1-351AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, IP, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000 |
| Примечание | Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Epigenetics and Nuclear Signaling, Cancer, Metabolism |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: E3 Ribonucleoside-diphosphate reductase subunit M2 B antibody at 6µg/ml
Lane 1: MCF-7 whole cell lysate
Lane 2: Hela whole cell lysate
Lane 3: HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 41, 35, 16, 8, 5, 49 kDa
Observed band size: 41 kDa
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Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA745339ESR1HU at dilution 1:100
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Наименование: RRM2B Antibody.