Объем | 50 мкл |
Синонимы | runt-related transcription factor 2 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q13950 |
Иммуноген | Synthetic peptide of human RUNX2 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Примечание | This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Epigenetics and Nuclear Signaling,Developmental biology,Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA694879(RUNX2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ?200)
|
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA694879(RUNX2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ?200)
|
| |