| Объем | 100 мкл |
| Синонимы | EC 6.2.1.7, FACVL3, FATP5, MGC143799, S27A5 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9Y2P5 |
| Иммуноген | Synthesized peptide derived from internal of human SLC27A5. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
| Примечание | Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol.<br/><br/>Steinberg S.J., Mol. Genet. Metab. 68:32-42(1999).<br/>Steinberg S.J., J. Biol. Chem. 275:15605-15608(2000).<br/>Mihalik S.J., J. Biol. Chem. 277:24771-24779(2002).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells, using SLC27A5 antibody.
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Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using SLC27A5 antibody.
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Immunofluorescence analysis of A549 cells, using SLC27A5 antibody.
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Наименование: SLC27A5 Antibody.