STAT5B AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Signal transducer and activator of transcription 5B | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P51692 | | Иммуноген | Fusion protein of human STAT5B | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, IHC,ELISA:1:500-1:10000, IHC:1:10-1:50 | | Примечание | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image is immunohistochemistry of paraffin-embedded Human lymphoma tissue using CSB-PA699319(STAT5B Antibody) at dilution 1/10. (Original magnification: ?200)
 | The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA699319(STAT5B Antibody) at dilution 1/10. (Original magnification: ?200)
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Наименование: STAT5B Antibody.