Объем | 100 мкл |
Синонимы | kinase GEK2, LOK, Lymphocyte-oriented kinase, Serine/threonine protein kinase 10, STK10 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O94804 |
Иммуноген | Synthesized peptide derived from internal of human STK10. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro, however such data require additional evidences in vivo.<br/><br/>Kuramochi S., Immunogenetics 49:369-375(1999).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>Schmutz J., Nature 431:268-274(2004).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HeLa cells and HuvEc cells, using STK10 antibody.
|
| |