TBXAS1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | CYP5, CYP5A1, Cytochrome P450 5A1, cytochrome P450, family 5 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P24557 | Иммуноген | Synthesized peptide derived from C-terminal of human THAS. | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, WB,WB:1:500-1:3000 | Примечание | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.<br/><br/>Yokoyama C., Biochem. Biophys. Res. Commun. 178:1479-1484(1991).<br/>Ohashi K., J. Biol. Chem. 267:789-793(1992).<br/>Miyata A., Eur. J. Biochem. 224:273-279(1994).<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Cancer,Cardiovascular,Cell biology,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Jurkat cells, using THAS antibody.
| | |
Информация для заказа |