| Объем | 100 мкг |
| Синонимы | Transcription factor E3 (Class E basic helix-loop-helix protein 33) (bHLHe33), TFE3, BHLHE33 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P19532 |
| Иммуноген | Recombinant Human Transcription factor E3 protein (1-110AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
| Примечание | Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Transcription factor E3 |
| Области исследований | Epigenetics and Nuclear Signaling, Cancer, Immunology |
| Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: 293 whole cell lysate
All lanes: TFE3 antibody at 2.7µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 62, 12 kDa
Observed band size: 62 kDa
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Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA023428LA01HU at dilution of 1:100
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Наименование: TFE3 Antibody.