| Объем | 100 мкл |
| Синонимы | Transcription factor E3, TFE3, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P19532 |
| Иммуноген | Synthesized peptide derived from internal of human TFE3. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.<br/><br/>Clark J., Oncogene 15:2233-2239(1997).<br/>Sidhar S.K., Hum. Mol. Genet. 5:1333-1338(1996).<br/>Beckmann H., Genes Dev. 4:167-179(1990).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Immunology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 cells and A549 cells, using TFE3 antibody.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue using TFE3 antibody.
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Наименование: TFE3 Antibody.