Объем | 50 мкл |
Синонимы | TIMP metallopeptidase inhibitor 1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P01033 |
Иммуноген | Fusion protein of human TIMP1 |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IHC,ELISA:1:1000-1:2000, IHC:1:15-1:50 |
Примечание | This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Cancer,Cardiovascular,Cell biology,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA827458(TIMP1 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA827458(TIMP1 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ?200)
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