TNFAIP1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | B12, B61, EDP1, MGC2317, TNAP1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q13829 | | Иммуноген | Synthesized peptide derived from internal of human TNAP1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.<br/><br/>Wolf F.W., J. Biol. Chem. 267:1317-1326(1992).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/>Nousiainen M., Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HUVEC cells treated with PMA (125ng/ml, 30mins), and HUVEC cells treated with serum (20%, 30mins), using TNAP1 antibody.
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Наименование: TNFAIP1 Antibody.