Объем | 100 мкл |
Синонимы | p53-binding protein 1, P531, TP53B, TP53BP1, TRP53BP1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q12888 |
Иммуноген | Synthesized peptide derived from Internal of human 53BP1. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.<br/><br/>Iwabuchi K., J. Biol. Chem. 273:26061-26068(1998).<br/>Nakajima D., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.<br/>Bechtel S., BMC Genomics 8:399-399(2007).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Cancer |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells and HUVEC cells, using 53BP1 (Ab-29) antibody.
|
Western blot analysis of extracts from 293 cells (Lane 2), using 53BP1 (Ab-29) antiobdy. The lane on the left is treated with synthesized peptide.
|
| |