Объем | 100 мкл |
Синонимы | DERMO1, MGC117334, bHLHa39 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q8WVJ9 |
Иммуноген | Peptide sequence around aa.26~30(P-K-R-F-G) derived from Human Twist2. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB,WB:1:500-1:1000 |
Примечание | <p>Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.</p><p>Lee M.S., Lowe G., Flanagan S., Kuchler K., Glackin C.A.Bone 27:591-602(2000)</p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Области исследований | Epigenetics and Nuclear Signaling,Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from A549, Hela and 3T3 cells using Twist2 Antibody.
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