UNC5B Antibody, Biotin conjugated

Спецификация

Объем	50 мкг
Синонимы	Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B) (p53-regulated receptor for death and life protein 1) (p53RDL1), UNC5B, P53RDL1 UNC5H2
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q8IZJ1
Иммуноген	Recombinant Human Netrin receptor UNC5B protein (404-517AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion (By similarity). Functions as netrin receptor that negatively regulates vascular branching during angiogenesis. Mediates retraction of tip cell filopodia on endothelial growth cones in response to netrin (By similarity). It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:12598906). Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity (By similarity).
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Netrin receptor UNC5B
Области исследований	Neuroscience, Cardiovascular, Signal transduction
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA025629LD01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: UNC5B Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).