VEGFA AntibodyСпецификацияОбъем | 50 мкл | Синонимы | vascular endothelial growth factor A | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P15692 | Иммуноген | Synthetic peptide of human VEGFA | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 | Примечание | This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Cancer,Cardiovascular,Developmental biology,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA379558(VEGFA Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
| The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA379558(VEGFA Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
| Gel: 12%SDS-PAGE, Lysate: 40 ?g, Lane 1-4: Hela cells, Jurkat cells, 293T cells, 231 cells, Primary antibody: CSB-PA379558(VEGFA Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 50 seconds
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