Объем | 100 мкг |
Синонимы | WW domain-containing adapter protein with coiled-coil, WAC, KIAA1844 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9BTA9 |
Иммуноген | Recombinant Human WW domain-containing adapter protein with coiled-coil protein (10-102AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IHC, IF, Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 |
Примечание | Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage. Positive regulator of amino acid starvation-induced autophagy. May negatively regulate the ubiquitin proteasome pathway. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | WW domain-containing adapter protein with coiled-coil |
Области исследований | Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA861133HA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA861133HA01HU at dilution of 1:100
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Immunofluorescent analysis of MCF-7 cells using CSB-PA861133HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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