XRCC3 Antibody, Biotin conjugated

Спецификация

Объем	50 мкг
Синонимы	DNA repair protein XRCC3 (X-ray repair cross-complementing protein 3), XRCC3
Клональность	Polyclonal Antibody
Организм	Human
uniprot	O43542
Иммуноген	Recombinant Human DNA repair protein XRCC3 protein (1-316AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the RAD21 paralog protein complex CX3 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, CX3 acts downstream of RAD51 recruitment, the complex binds predominantly to the intersection of the four duplex arms of the Holliday junction (HJ) and to junctions of replication forks. Involved in HJ resolution and thus in processing HR intermediates late in the DNA repair process, the function may be linked to the CX3 complex and seems to involve GEN1 during mitotic cell cycle progression. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	DNA repair protein XRCC3
Области исследований	Epigenetics and Nuclear Signaling, Cancer, Metabolism
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA026231LD01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: XRCC3 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).