Антитела VEGF (anti- VEGF antibody)VEGF (anti- VEGF antibody)СпецификацияClonality | polyclonal | Host | Rabbit | Specificity | Human, Mouse, Rat | Tested Application | ELISA, IHC, IF, WB | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | P15692 | Calculated MW | 23-27 kDa,45 kDa | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | Background | VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1(MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010). This antibody can recognize all the isoforms of VEFGA. | Immunogen | vascular endothelial growth factor A | Synonyms | L VEGFA, MVCD1, Vascular permeability factor, VEGF, VEGF A, VEGFA, VPF | Recommended dilution | WB: 1:200-1:2000; IP: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:50-1:500 | Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab09391(VEGFA Antibody) at dilution of 1:200
| PC-3 cells were subjected to SDS PAGE followed by western blot with FNab09391(VEGFA antibody) at dilution of 1:800
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Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100 мкг | Кат. номер: | FNab09391 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Антитела VEGF (anti- VEGF antibody) / VEGF (anti- VEGF antibody). Примечание: Clonality polyclonal, Host Rabbit, Specificity Human, Mouse, Rat,Tested Application ELISA, IHC, IF, WB |
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