anti- AGS3 antibody

Спецификация

Clonality	polyclonal
Host	Rabbit
Specificity	Human, Mouse, Rat
Tested Application	ELISA, IHC, IF, WB
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	Q86YR5
Calculated MW	72 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	GPSM1, also named as AGS3, is a receptor-independent G protein activator that has been implicated in multiple biological events such as brain development, neuroplasticity and addiction, cardiac function, Golgi structure/function, macroautophagy and metabolism. It contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory(GPR) motifs in its C-terminal half. It has been shown that AGS3 could regulate the orientation of the mitotic spindle, cAMP production, membrane protein transport, and asymmetric cell division by binding preferentially to inactive Gai/o subunits complexed with guanine dinucleotide phosphate(GDP) at multiple G-protein regulatory or GoLoco motif repeats. It also plays an important anti-apoptotic role through enhancing the phosphorylation of cyclic AMP response element-binding protein(p-CREB).
Immunogen	G-protein signaling modulator 1(AGS3-like, C. elegans)
Synonyms	AGS3, DKFZp727I051, GPSM1
Recommended dilution	WB: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:20-1:200
Immunohistochemistry of paraffin-embedded human lung cancer using FNab00221(GPSM1 antibody) at dilution of 1:50
HeLa cells were subjected to SDS PAGE followed by western blot with FNab00221(GPSM1 antibody) at dilution of 1:600

Информация для заказа

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab00221
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- AGS3 antibody. Примечание: