Clonality | polyclonal |
Host | Rabbit |
Specificity | Human, Mouse, Rat |
Tested Application | ELISA, WB, IHC |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | Q15389 |
Gene ID | |
Calculated MW | Refer to figures |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
Background | This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Immunogen | angiopoietin 1 |
Synonyms | AGP1, AGPT, ANG 1, ANG1, angiopoietin 1, ANGPT1, KIAA0003 |
Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100 |
Immunohistochemistry of paraffin-embedded human esophagus using FNab00391(ANGPT1 Antibody) at dilution of 1:100
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Immunohistochemistry of paraffin-embedded mouse lung using FNab00391(ANGPT1 Antibody) at dilution of 1:100
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