Clonality | polyclonal |
Host | Rabbit |
Specificity | Human, Mouse, Rat |
Tested Application | ELISA, WB, IHC |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | P12645 |
Gene ID | |
Calculated MW | 53 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
Background | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. |
Immunogen | bone morphogenetic protein 3 |
Synonyms | BMP3A |
Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:100 - 1:200 |
Immunohistochemistry of paraffin-embedded rat heart using FNab00918( BMP3 Antibody) at dilution of 1:50
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Recombinant protein were subjected to SDS PAGE followed by western blot with FNab00918( BMP3 Antibody) at dilution of 1:1000
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