anti- Acetylated tubulin(Lys40) antibodyСпецификация| Clonality | monoclonal | | Host | Mouse | | Specificity | Human, Mouse, Rat, Dog | | Tested Application | ELISA, WB, IHC, IF | | Delivery Time | 2 to 4 working days | | Clone ID | 6A10 | | Isotype | IgG1 | | Form | liquid | | Purification | Protein A+G purification | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | Q71U36 | | Gene ID | | | Calculated MW | 52 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Tubulin, composed of heterodimers of alpha and beta tubulin, is the mainly component of microtubules which play important roles in cell motility, mitosis, and intracellular vesicle transport. Both alpha and beta tubulin undergo several posttranslational modifications such as polyglutamylation and acetylation/deacetylation. Tubulin acetylation occurs on lysine-40 at the N-terminal of alpha tubulin and is conserved across species. The histone deacetylase HDAC6 and SIRT2 has been identified as tubulin deacetylases. Reversible acetylation of alpha tubulin may be implicated in regulating microtubule stability, cell motility, and axon regeneration. The level of acetylated tubulin has been linked to epithelial malignancies and sensitivity to chemotherapy. In addition, acetylated tubulin has been widely used as a marker for primary cilia. This antibody is specific to the acetylated tubulin; it does not recognize non-acetylated tubulin. | | Immunogen | tubulin, alpha 1a | | Synonyms | Acetylated alpha tubulin, Acetylated tubulin, acetylated-a-tubulin, acetyl-a-tubulin, alpha tubulin, Alpha tubulin 3, tubulin,TUBA1A | | Recommended dilution | WB: 1:500-1:5000; IF: 1:20-1:200; IHC: 1:20-1:200 | Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab00082(TUBA1A(ace-40Lys) Antibody) at dilution of 1:50
 | L02 cells were subjected to SDS PAGE followed by western blot with FNab00082(TUBA1A(ace-40Lys) Antibody) at dilution of 1:1000
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Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab00082 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- Acetylated tubulin(Lys40) antibody.
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