| Clonality | monoclonal |
| Host | Mouse |
| Specificity | Human |
| Tested Application | ELISA, WB, IF |
| Delivery Time | 2 to 4 working days |
| Clone ID | 6F3 |
| Isotype | IgG1 |
| Form | liquid |
| Purification | Protein A+G purification |
| Purity | ≥95% as determined by SDS-PAGE |
| Uniprot ID | P09972 |
| Calculated MW | 39 kDa |
| Ссылка на страницу на сайте производителя | ссылка |
| Инструкция | PDF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Background | Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097). |
| Immunogen | aldolase C, fructose-bisphosphate |
| Synonyms | ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C |
| Recommended dilution | WB: 1:5000-1:50000; IHC: 1:50-1:500; IF: 1:20-1:200 |
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab00304(ALDOC Antibody) at dilution of 1:200 . heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
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human heart tissue were subjected to SDS PAGE followed by western blot with FNab00304(ALDOC antibody) at dilution of 1:10000
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