Clonality | polyclonal |
Host | Rabbit |
Specificity | Human, Mouse, Rat |
Tested Application | ELISA, WB,IP |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | Q13367 |
Gene ID | |
Calculated MW | 120-140 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3(AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network(TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. |
Immunogen | adaptor-related protein complex 3, beta 2 subunit |
Synonyms | AP 3 complex subunit beta 2, AP3B2, Beta 3B adaptin, DKFZp686D17136, NAPTB |
Recommended dilution | WB: 1:200-1:2000
IP: 1:200-1:2000 |
rat brain tissue were subjected to SDS PAGE followed by western blot with FNab00464(AP3B2 Antibody) at dilution of 1:600
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