anti- BHLHE22 antibody

Спецификация

Clonality	polyclonal
Host	Rabbit
Specificity	Human, Mouse
Tested Application	ELISA, WB, IF
Delivery Time	2 to 4 working days
Isotype	IgG
Form	liquid
Purification	Immunogen affinity purified
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	Q8NFJ8
Gene ID
Calculated MW	37 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Inhibits DNA binding of TCF3/E47 homodimers and TCF3(E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA(By similarity). In the brain, may function as an area-specific transcription factor that regulates the postmitotic acquisition of area identities and elucidate the genetic hierarchy between progenitors and postmitotic neurons driving neocortical arealization. May be required for the survival of a specific population of inhibitory neurons in the superficial laminae of the spinal chord dorsal horn that may regulate pruritis. Seems to play a crucial role in the retinogenesis, in the specification of amacrine and bipolar subtypes. Forms with PRDM8 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation.
Immunogen	basic helix-loop-helix family, member e22
Synonyms	BHLHB5, TNRC20
Recommended dilution	WB: 1:200-1:1000; IF: 1:10-1:100
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab00887(BHLHE22 Antibody) at dilution of 1:300

Информация для заказа

Область использования: Поликлональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab00887
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- BHLHE22 antibody. Примечание: