anti- Caspase 10 antibodyСпецификацияClonality | polyclonal | Host | Rabbit | Specificity | Human | Tested Application | ELISA, WB, IHC, IF, IP | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | Q92851 | Gene ID | | Calculated MW | 59kd | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | Background | This gene encodes a protein which is a member of the cysteine-aspartic acid protease(caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. | Immunogen | caspase 10, apoptosis-related cysteine peptidase | Synonyms | ALPS2, Apoptotic protease Mch 4, CASP 10, CASP10, Caspase 10, Caspase 10/p23/17/p12, Caspase10, FLICE2, ICE like apoptotic protease 4, MCH4 | Recommended dilution | WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 | Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab01285(CASP10 antibody) at dilution of 1:100
| HeLa cells were subjected to SDS PAGE followed by western blot with FNab01285(CASP10 antibody) at dilution of 1:300
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Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab01285 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- Caspase 10 antibody. Примечание: |
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