anti- CD150 antibody(PE conjugated)СпецификацияClonality | monoclonal | Host | Rat | Specificity | Mouse | Tested Application | FC | Delivery Time | 2 to 4 working days | Clone ID | 3B6 | Isotype | IgG1 | Form | liquid | Purification | Protein G purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | Q9QUM4 | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | Background | CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM
(signalinglymphocyte activation molecule) orIPO-3. CD150, asingle chain type I transmembrane
molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells.
The expression is upregulated upon activation. CD150 expression has been shown to be
maintained onTh1 but notTh2 clones.Tregulatory cells express a relatively high level of CD150.
Antibodies against CD150 have been shown to augment IFN-g production byTh1 cells, especially
when co-stimulated through the TCR. CD150 associates with the src homology
2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be
involved in signal transduction. In combination with CD48, CD150 is a useful marker for
hematopoieticstem cell studies.
| Immunogen | signaling lymphocytic activation molecule family member 1 | Synonyms | CDw150, Slamf1, Slam, ESTM51, IPO-3, 4933415F16, AA177906 | Recommended dilution | 1:10-1:50 | | |
Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab09790 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- CD150 antibody(PE conjugated). Примечание: |
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