anti- CXCR3B-specific antibody

Спецификация

Clonality	monoclonal
Host	Mouse
Specificity	Human
Tested Application	ELISA, WB
Delivery Time	2 to 4 working days
Clone ID	6F7
Isotype	IgG1
Form	liquid
Purification	Protein A+G purification
Purity	≥95% as determined by SDS-PAGE
Uniprot ID	P49682
Calculated MW	40 kDa +43 kDa
Ссылка на страницу на сайте производителя	ссылка
Инструкция	PDF
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background	CXCR3(C-X-C chemokine receptor type 3) is a G protein-coupled, seven-transmembrane domain chemokine receptor that is expressed on the surface of a number of cell types, including activated CD4+ and CD8+ T cells, NK and NK-T cells, plasmacytoid dendritic cells, and some B cells(PMID: 16847335). CXCR3 binds and is activated by the three IFN-gamma-inducible chemokines: CXCL9, CXCL10, and CXCL11. Binding of these ligands to CXCR3 has been implicated in regulating T-cell infiltration during inflammation and tissue injury(PMID: 17250586). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms, CXCR3B, mediates the angiostatic activity of CXCR3 ligands and also acts as functional receptor for CXCL4(PMID:12782716). This monoclonal antibody is specific to CXCR3B.
Immunogen	chemokine(C-X-C motif) receptor 3
Synonyms	CD183, CKR L2, CMKAR3, CXC R3, CXCR 3, CXCR3, CXCR3A, CXCR3B, G protein coupled receptor 9, GPR9, IP 10 receptor, IP10 R, Mig R, MigR
Recommended dilution	WB: 1:500-1:5000
HeLa cells were subjected to SDS PAGE followed by western blot with FNab02101(CXCR3B antibody) at dilution of 1:2000

Информация для заказа

Область использования: Моноклональные антитела	Производство:	Fine Biotech
	Метод:	Антитела
	Объем:	100µg
	Кат. номер:	FNab02101
Цена (с НДС 20%):	по запросу	В корзину
Наименование: anti- CXCR3B-specific antibody. Примечание: