anti- CD14 antibodyСпецификация| Clonality | polyclonal | | Host | Rabbit | | Specificity | Human, Mouse, Rat | | Tested Application | ELISA, IHC, WB, IF, FC | | Delivery Time | 2 to 4 working days | | Isotype | IgG | | Form | liquid | | Purification | Immunogen affinity purified | | Purity | ≥95% as determined by SDS-PAGE | | Uniprot ID | P08571 | | Gene ID | | | Calculated MW | 50-55 kDa | | Ссылка на страницу на сайте производителя | ссылка | | Инструкция | PDF | | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | | Background | Coreceptor for bacterial lipopolysaccharide(PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide(LPS)(PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response(PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway(PubMed:16880211). | | Immunogen | CD14 molecule | | Synonyms | CD14, CD14 molecule | | Recommended dilution | WB: 1:500-1:1000; IHC: 1:100-1:400; IF: 1:50-1:500 | Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab01426(CD14 Antibody) at dilution of 1:200
 | HL-60 cells were subjected to SDS PAGE followed by western blot with FNab01426(CD14 Antibody) at dilution of 1:600
 | | | |
Информация для заказа| Область использования: | Производство: | Fine Biotech | | Метод: | Антитела | | Объем: | 100µg | | Кат. номер: | FNab01426 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: anti- CD14 antibody.
Примечание: |
|
